Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

Feature: U.S. needs national strategy to curb imaging overutilization

Medical imaging overutilization--a growing concern in the U.S.--exposes patients to unnecessary radiation, while also adding to rising healthcare costs, according to a study published online Aug. 24 in Radiology. In an interview, William R. Hendee, PhD, lead author, reviewed various methods by which medical imaging could be curtailed.

FDA weighs safety of Parkinson's therapy after possible CV risk found

The FDA is investigating the combination drug Stalevo (Novartis), used to treat Parkinsons disease, after results of the STRIDE-PD trial reported results that showed the drug may have the potential to increase cardiovascular risk in patients.

Radiology: Rad role may evolve as image-guided biopsies trend up

CT, ultrasound and MRI have helped shift biopsy techniques away from more invasive approaches toward image-guided percutaneous techniques, according to a study published in the September issue of Radiology. The trend toward less-invasive approaches translates into enhanced safety and efficiency and could lead to more interaction between patients and radiologists.

JACC: Two-device option increases suitability for arotic valve implantation

For patients with severe aortic stenosis, offering either the Edwards Lifesciences Sapian or Medtronic CoreValve devices allows a greater number of patients to be suitable for transcatheter aortic valve implantation, according to a study published in the August edition of the Journal of the American College of Cardiology: Cardiovascular Interventions.

Webinar: Changes in store for Interoperability Showcase, IHE Connectathon

Changes are comnig to the 2011 Interoperability Showcase and Connectathon events, said Celina Roth, HIMSS manager of informatics, IHE Secretariat, during a IHE [IIntegrating the Healthcare Experience] webinar Aug. 17.

EHJ: Cards need to bone up on mitral valve regurgitation guidelines

Guidelines suggest repair rather than replacement should be the first course of action for asymptomatic severe mitral valve regurgitation, but more often it is not. Researchers suggest that cardiologists should become more familiar with the guidelines to ensure proper surgical referral, according to a study in the Aug. 16 edition of the European Heart Journal.

Wyeth acquisition, international Lipitor sales help Pfizer's Q2

Pfizer has reported financial results for second quarter of 2010, which reflect legacy Wyeth products and operations that are not reflected in the first two quarters of 2009, since the Wyeth acquisition was completed in late 2009.

FDA may withdraw low blood pressure drug from U.S. market

The FDA is proposing to withdraw approval of the drug midodrine hydrochloride, used to treat the low blood pressure condition orthostatic hypotension, because required post-approval studies that verify the clinical benefit of the drug have not been done.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

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