Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

Study: Generic diuretics = branded hypertension drugs

Hypertension therapies, ACE inhibitors and calcium channel blockers are more expensive and may be no better than using a generic diuretic for preventing cardiovascular disease, according to the results of a substudy of the ALLHAT trial presented Aug. 13 at the China Heart Congress and International Heart Forum in Beijing.

Defibtech, SCAA continue partnership to donate AEDs in critical areas

Defibtech, a maker of automated external defibrillators (AEDs), and the Sudden Cardiac Arrest Association (SCAA) have teamed up for the third straight year to donate AEDs in communities with critical needs.

Pennsylvania Amish community gets onboard with AED program

Underscoring that a sudden cardiac arrest emergency requires quick response and that automated external defibrillators (AEDs) are easy to use, the Eastern Pennsylvania Chapter of the Sudden Cardiac Arrest Association (SCAA) has launched a unique community response team with the Amish community of Lancaster County, Pa., at the center of a broad program that will deploy AEDs in public locations, schools and even on horse and buggies and Amish farms.

Lancet: CRESCENDO halted after diet pill linked to suicides

Rimonabant (Acomplia, Sanofi-Aventis), a cannabinoid-1 receptor antagonist, was developed as a weight loss drug to diminish waist circumference and bodyweight; however, while researchers were studying the efficacy of the drug to also reduce vascular events, they found that it increased the incidence rates of neuropsychiatric effects, including suicide.

Medicare beneficiaries stuck in donut hole get rebate checks

Eligible Medicare beneficiaries who land in the Medicare Part D donut hole may be getting some relief in their mailboxes--a one-time, tax-free $250 rebate check issued by the U.S. Department of Health and Human Services (HHS) as part of the Patient Protection and Affordable Care Act.

Circulation: Cooling times & methods for cardiac arrest remain uncertain

Cooling cardiac arrest patients with IV ice-cold solution en route to the hospital did not improve outcomes at hospital discharge compared with patients whose cooling commenced in the hospital. Researchers not only question the timing but also the method of cooling, according to a study published online Aug. 2 in Circulation.

Merck income drops 51% in Q2, despite strong CV drug sales

Merck has reported a 51 percent reduction in its net income for the second quarter of 2010, which ended June 30, due to internal expenses.

Medicines Co. wins one-year patent extension for Angiomax

The U.S. Patent and Trademark Office has granted The Medicines Company a one-year extension for its patent (Patent No. 5,196,404), covering its antithrombotic agent bivalirudin (Angiomax).

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

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