Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

CPR quality better at scene, rather than in transport

In a study of two EMS agencies, researchers found an increase in the variability of chest compression quality for the rate and depth of compressions during the ground transport of cardiac arrest patients, according to a study presented in January at the 2010 National Association of EMS Physicians (NAEMSP) conference in Phoenix, Ariz.

Sanofi inks $335M diabetes deal

CureDM and pharmacuetical company Sanofi-Aventis have signed an agreement for the licensing of CureDMs Pancreate, an islet neogenesis agent for the treatment of type 1 and 2 diabetes.

AHA: Temp-dependent drug may prevent blood clots during hypothermia

To prevent blood clots during therapeutic hypothermia, researchers have developed what may be the first drug activated by cool temperatures and turned off by warm ones, according to research presented April 9 at the American Heart Association's 2010 Arteriosclerosis, Thrombosis and Vascular Biology annual conference in San Fransisco.

Circulation: Transcatheter valve-in-valve implants are 98% effective

When bioprosthetic valves fail, transcatheter valve-in-valve implantation may be a viable option used to mend aortic, pulmonary, mitral and tricuspid tissue valves, based on a study published in Circulation on April 12.

Bancroft becomes permanent CFO at Bristol-Myers

Bristol-Myers Squibb (BMS) has selected Charles Bancroft to serve as its permanent chief financial officer (CFO).

Case Study: Columbia discovers fiscal benefits with clinical trial oversight

At Columbia University Medical Center in New York City, prior to the overhaul of its previous Clinical Trial Management Solution, the facility held minimal oversight over its payment cycle and information on sponsored clinical trials was not available and unaccounted for, said Susan Adler, research applications administer of the clinical trials office at Columbia during a webinar yesterday sponsored by StudyManager.

Pharma paid Vermont providers $2.6M in FY09drop from prior year

In the twelve months before July 1, 2009, 85 pharmaceutical manufacturers paid about $2.6 million to Vermont doctors, hospitals, universities and others for the purpose of marketing their drugs. This was a drop from nearly $3 million the previous fiscal year.

AstraZeneca vindicated in Seroquel court decision

The 11th Circuit Appellate Court has upheld a lower court decision to grant AstraZeneca's summary judgment and dismiss the first product liability case that had been prepared for trial in the quetiapine (Seroquel) federal Multi-District Litigation.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

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