Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

Q&A: Preventing Infections Before, During and After Procedures

While your facility likely has robust measures in place to dodge contamination, recent developments provide a valuable reminder to examine current practices.

ESC: Higher-dose Pradaxa in a-fib patients fares better than warfarin

In atrial fibrillation patients, dabigatran (Pradaxa) administered at 110 mg was associated with similar rates of stroke and systemic embolism as with warfarin, as well as lower rates of major hemorrhage, based on the RE-LY trial presented Sunday at the European Society of Cardiology (ESC) Congress in Barcelona, Spain. Yet, dabigatran administered at 150 mg, compared with warfarin, was associated with lower rates of stroke and systemic embolism but similar rates of major hemorrhage.

Takeda starts trial to assess cardiovascular risks with diabetes drug

Takeda Pharmaceutical Company Limited and its U.S. subsidiary Takeda Global Research & Development Center in Deerfield, Ill., have received notification that the FDA has agreed to the study design for EXAMINE, a cardiovascular outcomes trial for alogliptin, a selective dipeptidyl peptidase IV inhibitor under investigation for the treatment of type 2 diabetes as an adjunct to diet and exercise.

JACC: Beta blockers can have damaging effect on the elderly

Researchers may have uncovered the reason why beta blockers are less effective at preventing stroke in older people with high blood pressure, when compared to other drugs for high blood pressure.

AJMC: e-Reminder helps discharged patients manage LDL-C

Low-density lipoprotein cholesterol (LDL-C) and blood pressure measures can remain controlled in most patients discharged from a cardiac disease management program, according to a randomized study in Augusts American Journal of Managed Care.

Medtronic income drops 38%, despite slight revenue increase

Medtronic has reported a decline in net income of financial results for its recent quarter, compared to a year ago.

More AEDs for Responders, Less Time with Refractory OHCA

Sudden cardiac arrest (SCA) survivor Chris Knight likes to say he died five times in one day and, in fact, he did. Knights heart stopped four more times after an initial SCA. Luckily for him, the city in Illinois where he was visiting equips all its police officers and first responders with automated external defibrillators (AEDs). His experience has made him into a crusader to have AEDs for all first responders in his part of the Texas Panhandle.

BMJ: Actos leads to less heart failure, death compared with Avandia

Among older patients with diabetes, pioglitazone (Actos) is associated with a significantly lower risk of heart failure and death than is rosiglitazone (Avandia), according to a retrospective cohort study published Aug. 18 in the British Medical Journal.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

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