Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

Strong diabetes drug sales, less spending thrust Merck into positive Q3

Merck has reported a strong net income for the third quarter of 2009, which ended Sept. 30.

SCCA honors efforts to address sudden cardiac arrest

October is Sudden Cardiac Arrest Awareness Month, and the Sudden Cardiac Arrest Association (SCAA) has awarded its 2009 leadership awards, going to the New York City Fire Department and the governor of Illinois, among others.

SCA is to a heart attack like apples are to oranges

October is sudden cardiac arrest (SCA) awareness month and the Heart Rhythm Society has begun a campaign to educate the public about the difference between a heart attack and SCA and to educate physicians about better informing their patients of these differences.

Pfizers Q3 income rose, despite lower Lipitor sales

Pfizer has reported a double-digit increase in net income for the 2009 third quarter, despite falling cardiovascular pharmaceutical sales.

Pressure on hypertension meds rises

While many studies continue to evaluate the current crop of statins and angiotensin-converting enzyme (ACE) inhibitors, some researchers have their eyes on the next generation of combination therapies using these two classes of drugs.

Sanofi cozies up to Wellstat for $350M diabetes insulin pact

Wellstat Therapeutics and Sanofi Aventis have signed a global licensing agreement to develop, manufacture and commercialize PN2034, an oral insulin sensitizer for the treatment of type 2 diabetes. PN2034 was discovered by Wellstat and is currently in Phase II clinical trials to reverse insulin resistance in the liver of diabetic patients.

Merck becomes second Big Pharma company to disclose doc payments

Merck has begun disclosing payments to U.S. medical and scientific professionals who speak on behalf of the company or its products, detailing approximately $3.7 million in payments for the third quarter, as part of its voluntary commitment to increase transparency.

JACC: Medtronics transcatheter pulmonary valve shows promise

Implantation of the Melody transcatheter pulmonary valve (Medtronic, Minneapolis) for right ventricular outflow tract conduit dysfunction can be performed by experienced operators at multiple centers, appears safe, and has encouraging acute and short-term outcomes, according to a study in the Oct. 27 issue of the Journal of the American College of Cardiology.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Trimed Popup
Trimed Popup