Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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Medtronic announces 2 new TAVR studies, including a head-to-head comparison of Evolut Pro and Sapien 3

A new feasibility study focused on additional patient populations is also in the works.

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Valve durability after 5 years: Sapien 3 TAVR outcomes comparable to SAVR

The Sapien 3 prosthesis continues to impress, though researchers must continue to monitor its performance as time goes on.

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TAVR safe for low-risk patients with bicuspid aortic valve disease

More research on long-term outcomes is still needed before TAVR can be recommended for such patients across the board.

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How COVID-related delays are impacting TAVR patients

Some high-risk patients died during the delay, the research team reported. 

New study highlights the benefits of treating aortic stenosis, CAD with TAVR instead of surgery

Patients who received TAVR and PCI experienced lower rates of mortality and fewer major bleeding events than those treated with SAVR and CABG. 

TAVR outcomes after 1 year much worse for patients with valvular AFib

The study focused on more than 1,400 TAVR patients treated from August 2007 to June 2018. 

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Bicuspid aortic valve repair leads to 'excellent' long-term outcomes

Overall, the team behind the study noted a survival rate of 82.1% after 15 years. 

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The unlikely relationship between TAVR and chronic kidney disease

“The findings of this study will influence shared decision-making between chronic kidney disease patients and the heart team,” one specialist observed. 

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.