Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

FDA grants breakthrough device designation to Medtronic TTVR system, approves early feasibility study

According to Medtronic, its Intrepid TTVR system helps meet a “large, unmet clinical need.”

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Endocarditis after TAVR: Increasingly rare, but incredibly fatal

The authors examined data from more than 134,000 TAVR patients, noting that 65% of endocarditis infections occurred within one year after the procedure. 

heart valve 3d printed

3D-printed heart valve models have the feel and look of the real thing

The patient-specific models were designed to help clinicians prepare for transcatheter aortic valve replacement (TAVR) procedures.

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Gout medication could be used to treat congenital heart disease

Treatment with probenecid led to “improved cardiac function and exercise performance” in patients with congenital univentricular circulation.

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TAVR outcomes similar after conscious sedation and general anesthesia

The new research out of Germany suggests both strategies are safe and effective for patients. 

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A historic first: Researchers grow functional heart model the size of a sesame seed

The cardiac models were created using human stem cells. Each one is able to beat in less than a week. 

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How population density can influence TAVR utilization, patient outcomes

Patient access to TAVR centers is often limited in rural areas where resources are in short supply.

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How patient-specific simulations can improve TAVR care

Overall, the simulations inspired clinicians to change part of the treatment plan for 16 of 42 patients.  

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.