Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

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Early placement of Abiomed's Impella 2.5 increases survival rate in cardiogenic shock patients

New research on a heart pump designed to treat cardiogenic shock patients receiving a percutaneous coronary intervention (PCI) suggests that early placement of the device can boost survival rates.

U.S. FDA Grants Priority Review of XARELTO (rivaroxaban) sNDA for a 10 mg Dose to Reduce the Risk of Recurrent Venous Thromboembolism

RARITAN, N.J., June 28, 2017 /PRNewswire/ -- Janssen Research & Development, LLC announced today the U.S. Food and Drug Administration (FDA) accepted for Priority Review a supplemental New Drug Application (sNDA) for XARELTO® (rivaroxaban) to include a 10 mg once-daily dose for reducing the risk of VTE after at least six months of standard anticoagulant therapy. This application is based on data from EINSTEIN CHOICE, which is the only study to find a non-vitamin K antagonist oral anticoagulant (NOAC), specifically two doses of XARELTO® (10 mg and 20 mg), to be superior to aspirin in reducing the risk of recurrent VTE, with comparable rates of major bleeding.

Bayer Now Enrolling Patients into a Global Pulmonary Arterial Hypertension Study

WHIPPANY, N.J., June 29, 2017 /PRNewswire/ -- Bayer has enrolled the first patient in a global Phase IV study assessing the clinical effects of riociguat in patients with pulmonary arterial hypertension (PAH), who were being treated with a Phosphodiesterase-5 inhibitors(PDE-5 inhibitors), either as monotherapy or in combination with an endothelin receptor antagonist (ERA), and who did not reach their therapeutic goal. The study, which is a part of the collaboration between Bayer and Merck, is seeking to enroll patients at 26 sites in the U.S. with a total of 100 study sites worldwide.

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A Practical Guide to Palliative Care for Heart Failure Patients

With a few practical steps, cardiology practices can meet the palliative care needs of heart failure patients.

Researchers pinpoint why some don't respond to beta-blockers

New research may show why some heart failure patients don’t respond to beta-blocker drugs—with the cause lying in the dysfunction of beta-adrenergic receptor 3 (β3AR) and resulting decreases in cardioprotective phospholipid.

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Making the Call for Closure: Heart–Brain Teams Strive to Improve Patient Selection for PFO Closure

Did the patent foramen ovale (PFO) cause the patient’s stroke? This, experts say, is the key question when deciding whether to recommend PFO closure. Heart–brain teams can help with the answer.   

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Adjunctive Diagnostics in the Cath Lab: Will Value-based Economics Tip the Scale?

Why has the uptake of adjunctive diagnostic procedures like FFR, IVUS and OCT been slow? On the other hand, is there really a need for interventionalists to move beyond angiographic guidance?

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Black heart failure patients hospitalized twice as often as whites

Though the rate of heart failure hospitalizations has decreased over the last few years in the U.S., black Americans are still admitted at a higher rate than other ethnic and racial groups, according to a new study from the University of California, Los Angeles.

Around the web

Several key trends were evident at the Radiological Society of North America 2024 meeting, including new CT and MR technology and evolving adoption of artificial intelligence.

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.