Nuclear Medicine

Nuclear medicine (also called molecular imaging) includes positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. Nuclear imaging is achieved by injecting small amounts of radioactive material (radiopharmaceuticals) into patients before or during their scan. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

A study published this week in the Journal of the American College of Cardiology (JACC): Cardiovascular Imaging shows artificial intelligence (AI) algorithms can more rapidly and objectively determine calcium scores in computed tomographic (CT) and positron emission tomographic (PET) images than physicians.[1] The AI also performed well when the images were obtained from very-low-radiation CT attenuation scans. https://doi.org/10.1016/j.jcmg.2022.06.006

Artificial intelligence can objectively determine cardiac calcium scores faster than doctors

A new study shows artificial intelligence (AI) algorithms can more rapidly and objectively determine calcium scores in CT and PET/CT images than physicians.

Comparison of flurpiridaz F-18 PET, SPECT and angiography of the 60-year-old female patients in the Aurora trial. The SPECT scan appeared normal, but flurpiridaz was shown to be more sensitive and showed the ischemia from two blockages in the right coronary artery. The new radiotracer may help expand cardiac PET. #ASNC

Flurpiridaz data shows promise to expand and enhance cardiac PET

The biggest news from the American Society of Nuclear Cardiology (ASNC) 2022 meeting was positive late-breaking data on the phase 3 Aurora trial for the flurpiridaz (F-18) PET radiotracer agent.

PET imaging uncovers a surprising new way COVID-19 affects the heart

A new study in JACC: Cardiovascular Imaging focuses on a potential new side effect of COVID-19, highlighting the continued importance of monitoring these patients going forward. 

COVID-19 medical imaging examples of various clinical presentations. SARS-CoV-2 clinical imaging presentations.

PHOTO GALLERY: What does COVID-19 look like on medical imaging?

This image gallery shows what the various clinical presentations associated with the COVID-19 virus that have been documented during the coronavirus pandemic.

Big private payer reverses course on cardiac PET/CT coverage

One of the largest private health insurers in the U.S. has gone from considering hybrid PET/CT for cardiac indications “experimental/investigational” to displaying willingness to pay for the modality. 

The American Medical Association (AMA) Board of Delegates approved a policy calling on payers to reimburse for the drug regadenoson and not to employ payment policies that push for cardiologists to change the drug they use for pharmacologic stress for one that is considered less safe. The policy was adopted at the AMA 2022 meeting. #AMA #AMA175 #AMAmtg #ASNC

AMA supports reimbursement for pharmacologic stress agent regadenoson

The American Medical Association Board of Delegates approved a policy calling on payers to reimburse for the drug regadenoson and not to employ payment policies that push for cardiologists to change the drug they use for pharmacologic stress for one that is considered less safe.

Researchers have designed a new cardiac SPECT imaging system that could potentially deliver images much faster than current models. The team presented its findings at the annual meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), SNMMI 2022.

The need for speed: New-look cardiac SPECT imaging system could be up to 100 times faster than current models

Researchers presented their proposed design of a self-collimating SPECT system at SNMMI 2022.

SNMMI Image of the Year 68Ga-FAPI-46 PET/CT heart attack acute myocardial infarction

‘Image of the Year’ highlights the predictive power of a new PET imaging agent

The Society of Nuclear Medicine and Molecular Imaging has chosen its 2022 Image of the Year, and it’s one that is sure to interest anyone in the field of cardiac imaging.

Around the web

Several key trends were evident at the Radiological Society of North America 2024 meeting, including new CT and MR technology and evolving adoption of artificial intelligence.

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.