Medtronic Completes Acquisition of Twelve, Inc.

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DUBLIN - October 2, 2015 - Medtronic plc (NYSE: MDT) today announced that it has completed the acquisition of Twelve, Inc. ("Twelve"), a privately-held medical device company based in Redwood City, CA, focused on the development of a transcatheter mitral valve replacement (TMVR) device.

"This acquisition supports Medtronic's therapy innovation strategy, as TMVR represents an important growth opportunity for our business," said Sean Salmon, senior vice president and president, Coronary & Structural Heart, Medtronic. "We look forward to welcoming the Twelve team to Medtronic to help deliver an exciting and differentiated therapy to patients."

In collaboration with leading clinicians, researchers and scientists worldwide, Medtronic offers the broadest range of innovative medical technology for the interventional and surgical treatment of cardiovascular disease and cardiac arrhythmias. The company strives to offer products and services that deliver clinical and economic value to healthcare consumers and providers around the world.

The Medtronic TMVR technology is not available for sale in any country.

About Medtronic
Medtronic plc (www.medtronic.com), headquartered in Dublin, Ireland, is among the world's largest medical technology, services and solutions companies - alleviating pain, restoring health and extending life for millions of people around the world. Medtronic employs more than 85,000 people worldwide, serving physicians, hospitals and patients in more than 160 countries. The company is focused on collaborating with stakeholders around the world to take healthcare Further, Together.

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