Clinical Research

Scientists identify a potential new treatment for vascular dementia
“Patients are in desperate need of an effective treatment, and we are doing everything we can to help find that treatment,” one scientist explained. “The greatest reward would be to see a safe and effective treatment for people who currently have very few options.”
Government-funded program wants better AI for managing heart failure in the US
The long-term goal is to bring 24-7 cardiac care to every American, even those living in counties with no cardiologists.
Acoramidis bests tafamidis in head-to-head comparison of ATTR-CM drugs
Acoramidis was associated with a 43% lower risk of diuretic intensification and a 34% lower risk of clinical worsening overall.
TAVR timing: Waiting more than 6 months may hurt survival odds
When heart patients are diagnosed with severe AS, how quickly do they need to undergo TAVR? That was the focus of a new analysis published in Open Heart.
European Society of Cardiology joins effort to improve access to heart data
Accessing cardiology data for research or population health initiatives is still quite difficult in Europe. Could this new project help reverse that trend?

New imaging protocols proposed to curb rise of cardiovascular infections

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Ultra-processed foods linked to 32 adverse health outcomes, including CVD-related death and diabetes

Data from nearly 9.9 million participants were included in the team’s final analysis. The group emphasized the important role governments can play in trying to reverse the world's reliance on these products.

Left, the FIRE1 heart failure remote monitoring device that gets implanted into the IVC to measure fluid volume status. Right, the external belt monitoring device worn by the patient that can alert clinicians about status changes so interventions can be done before a patient requires a hospital admission.

Early feasibility study for implantable heart failure monitor moves forward

Startup vendor FIRE1 completed patient enrollment in its U.S. early feasibility study for a heart failure remote monitoring device that directly measures fluid volume inside the IVC.

Using the Sentinel cerebral protection device during valve-in-valve TAVR is associated with significant clinical improvements.

Cerebral protection devices during valve-in-valve TAVR: Cleveland Clinic cardiologists identify key benefits

Cerebral protection devices, designed to limit the risk of stroke during transcatheter aortic valve replacement, may be especially helpful when patients undergo valve-in-valve TAVR.

Multiple factors can interfere with pulse oximetry accuracy including skin pigmentation. Multiple studies have shown the inaccuracy of current pulse oximeters in patients with darker skin tones than whites, often over estimating their oxygenation when in fact they are hypoxic. Images courtesy of Masimo.

Inaccurate pulse oximeter readings impact Black heart failure patients and FDA plans to address this

Black patients are already less likely to receive LVADs or transplants compared to whites, and these inaccurate readings can further widen the disparities.