Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

How one center boosted palliative care use for advanced heart failure patients

A nurse navigator-led program at Providence St. Vincent Medical Center in Oregon helped the hospital double its palliative care referral rates for advanced heart failure patients considered to be at high risk of readmission.

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6 months after OHSU heart transplant program implodes, Providence offers a helping hand

Oregon Health & Sciences University might have a chance to revive the heart transplant program it shuttered last August after all four of its cardiologists left the institution, according to reports from the Oregonian and Oregon Live.

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Left ventricular function helps predict post-op mortality in HF patients

Heart failure (HF)—both symptomatic and asymptomatic—is associated with an up to 10 percent increased risk of 90-day postoperative mortality in patients undergoing noncardiac surgery, according to a study published Feb. 12 in the Journal of the American Medical Association.

His-optimized CRT improves electrical resynchronization in advanced HF patients

His-optimized cardiac resynchronization therapy successfully narrowed QRS duration, improved left ventricular (LV) ejection fraction and heightened functionality in 27 patients with advanced heart failure (HF), according to a study published in Circulation: Arrhythmia and Electrophysiology.

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Almost 25% of HFrEF patients prescribed drugs that could worsen their condition

Nearly a quarter of adults living with heart failure with reduced ejection fraction (HFrEF) are prescribed at least one pharmaceutical that could exacerbate their condition, according to a study published in the American Journal of Cardiology Feb. 10.

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Optimal hemodynamics reduce HF readmissions in LVAD patients

Optimizing hemodynamics for heart failure (HF) patients with continuous-flow left ventricular assist devices (LVADs) significantly reduces the rate of those patients’ hospital readmissions, according to a study published Feb. 1 in Circulation: Heart Failure.

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Postmarket mortality for Impella RP exceeds rate from earlier trials

Survival rates for patients treated with Abiomed’s Impella RP right ventricular assist device have been much lower in a postapproval study than they were during the device’s premarket clinical trials, the FDA said Feb. 4 in a letter to physicians.  

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Some chemo drugs might be more heart-safe than others

Current conversion ratios may be underestimating the long-term cardiotoxicity of common chemotherapy agents like mitoxantrone and overestimating the cardiovascular risk of anthracyclines like daunorubicin, researchers reported in JAMA Oncology Jan. 31.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.