Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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CroíValve DUO device tricuspid valve

CroíValve kicks off early feasibility study for new TR device, names cardiologist Martin Leon to advisory board

The company hopes to enroll 15 patients to monitor the safety and effectiveness of its new-look transcatheter device for severe tricuspid regurgitation. 

Tootsie Roll paravalvular leak transcatheter heart valves

New ‘Tootsie Roll’ technique could help cardiologists treat PVL in transcatheter heart valves

Paravalvular leak remains a significant problem after TAVR, SAVR and even TMVR. Could a new-look interventional technique help heart teams overcome this issue and improve patient outcomes? 

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An updated look at combining LAAO with ablation, TAVR or other interventional heart procedures

Performing two procedures at once does not appear to make a significant impact on patient safety, though it may lead to a few new risks sure to interest heart teams. 

Pi-Cardia ShortCut TAVR device

FDA grants new valve-in-valve TAVR offering its breakthrough device designation

The new device was designed to help clinicians perform valve-in-valve TAVR on certain high-risk patients. One cardiologist familiar with the technology said it could be easily added to any preexisting TAVR workflow. 

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Valve-in-valve TAVR with Medtronic’s CoreValve devices still safe and effective after 5 years

Researchers tracked five-year data from more than 200 patients, sharing their findings in the American Journal of Cardiology.

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TAVR in patients with severe obesity: Longer hospital stays, higher costs, more health risks

The CDC defines severe obesity, or class III obesity, as any patient with a BMI of 40 or higher. TAVR among these patients is not associated with a lower survival rate, but it does lead to many more risks.

ICE-guided Watchman procedures linked to safety concerns—is TEE better for LAAO or will things improve?

TEE and ICE are each associated with certain advantages and disadvantages, researchers explained. The new analysis included data from nearly 40,000 patients.

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Integer acquires medical device specialists with experience in structural heart, electrophysiology for $140M

Integer's estimated 2023 sales nearly reached $1.6 billion, up 16% compared to 2022. According to the company's statement, this acquisition helps expand its footprint in several key markets. 

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Around the web

Health Imaging
Use of AI opportunistic screening in CT for cardiovascular disease

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Health Imaging
New imaging protocols proposed to curb rise of cardiovascular infections

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

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