Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

Innovalve Bio Medical's Innostay TMVR device. Edwards Lifesciences has agreed to acquire Innovalve after an initial investment in 2017.

Edwards Lifesciences to acquire medical device startup behind new TMVR technology

Edwards, an early investor when the company first launched in 2017, said the acquisition will ensure its TMVR platform reaches as many patients as possible. 

Boston Scientific ACURATE neo2 aortic valve system self-expanding TAVR valve

Boston Scientific TAVR valve linked to positive outcomes after next-day discharge

The self-expanding valve is not yet approved by the FDA, but care teams in other markets are reporting positive outcomes when patients go home the day after treatment. 

cardiologist viewing heart data

TAVR and pulmonary hypertension: Key details from a study of 35,000 patients

Patients with pulmonary hypertension are associated with increased short- and long-term risks of death following TAVR. Researchers emphasized the importance of learning as much as possible about this topic going forward. 

dollar money graph increase finance

Market for transcatheter heart valve replacement could top $19B in 10 years

As one may expect, advances in TAVR and TMVR technologies are seen as key drivers of the market’s success.

Surgeons Operating On Patient

Mechanical valves linked to superior long-term survival after tricuspid valve replacement

Each valve type has its own benefits, researchers noted, but mechanical valves are associated with multiple long-term benefits compared to tissue/bioprosthetic valves. 

doctor with overweight patient who may be treated with TAVR or surgery

How persistent AFib impacts TAVR survival

Persistent and paroxysmal atrial fibrillation appear to affect short- and long-term TAVR mortality rates in different ways, according to a new study of nearly 3,000 patients. Some trends fade over time, while others remain in place after many years. 

artificial intelligence in cardiology

AI can help cardiologists predict death after TAVR—but there is a catch

It's clear that advanced AI algorithms will radically transform care for TAVR patients in the years ahead. For now, however, certain AI models may require too much data to be helpful on a consistent basis. 

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The waiting game: Delaying TAVR increases healthcare costs by $10K per year

Delaying TAVR in eligible patients with severe AS can lead to much higher healthcare costs, according to a new study of real-world Medicare data.

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