Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

USA Volleyball staff get CPR, AED training

In recognizing both the chance of adverse cardiac events associated with sporting events and the value of CPR and automated external defibrillators (AEDs) to help save lives, 15 members of USA Volleyball this month completed the American Heart Association's first aid certification.

Circ: Brief video training boosts hands-only CPR attempts

Study participants who viewed a brief hands-only CPR video were more likely to attempt CPR, and perform better quality CPR in an emergency than participants who did not view the short videos, according to research reported in the April issue of Circulation: Cardiovascular Quality and Outcomes.

Risk Stratification for CV Disease Gets Personal

Stratifying cardiac disease risk is evolving along with the advancements in imaging technology, which help risk stratification become more highly individualized, taking us further toward personalized medicine.

Managing Chronic Angina: What Do We Know?

While there are a multitude of drugs and lifestyle changes that are prescribed for chronic angina, properly managing this patient population continues to challenge cardiologists. However, recent studies have begun to reveal new therapies that might better relieve this chronic pain.

NEJM: Actos prevents diabetes in 72% of pre-diabetics

Compared with placebo, pioglitazone (Actos, Takeda Pharmaceuticals) reduced the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72 percent, but was associated with significant weight gain and edema, according to a study published March 24 in the New England Journal of Medicine.

JCL: LDL-P levels may better predict CVD risk than cholesterol

LDL-particles (LDL-P) can better predict atherosclerotic risk and cardiovascular disease (CVD) risk when LDL-P and LDL-cholesterol (LDL-C) were discordant, according to a study published in the March-April issue of the Journal of Clinical Lipidology.

JAMA Feature: More sensitive troponin test IDs more at risk of MI

In patients with suspected acute coronary syndrome (ACS), implementation of a sensitive troponin assay increased the diagnosis of MI and identified patients at high risk of recurrent MI and death in the following year, according to a study in the March 23/30 issue of the Journal of the American Medical Association. However, one researcher expresses caution about lowering the troponin threshold for MI.

Takeda, Amylin halt obesity drug trial

Amylin Pharmaceuticals and Takeda Pharmaceutical have suspended clinical activities in an ongoing phase II study examining the safety and effectiveness of the investigational combination therapy pramlintide/metreleptin for the treatment of obesity.

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