Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

JACC: Extreme glucose levels in diabetics with heart failure increases risk of death

Compared with patients with moderately controlled glucose levels, diabetic patients who have heart failure and either too high or too low glucose levels may be at increased risk of death, according to a retrospective study published online July 17 in the Journal of the American College of Cardiology.

Baxter has strong Q2, raises outlook for Q3

Baxter International has reported strong financial results for the second quarter of 2009, causing the company to raise its third quarter financial outlook.

Merck settles with 35 states for $5.4M over Vytorin, Zetia marketing

Merck and Schering-Plough, along with their joint venture, Merck/Schering-Plough Pharmaceuticals, have reached a civil settlement of $5.4 million with a group of attorneys general representing 35 states and Washington, D.C., who investigated whether the companies violated state consumer protection laws in connection with the ENHANCE trial or by their promotion and marketing of Vytorin and Zetia.

Aurobino receives FDA nod for generic hypertension drug

Aurobindo Pharma has received approval from the FDA for Fosinopril Sodium and hydrochlorothiazide (HCT) tablets, a generic equivalent of Bristol-Myers Squibb's ACE inhibitor Monopril HCT.

FDA greenlights prasugrel, after one-year delay

The FDA this afternoon approved Daiichi Sankyo and Eli Lilly's Effient (prasugrel) tablets for the reduction of thrombotic cardiovascular events, including stent thrombosis, in patients with acute coronary syndromes who are managed with PCI.

AHA launches first iPhone app: First aid & CPR

Emergency information is just one touch away with the American Heart Association's new Pocket First Aid & CPR application for the Apple iPhone, released July 9.

Report: U.S. pays 40% more for top selling drugs, compared to EU

European prices of 170 best selling drugs averaged 40 percent less than U.S. prices in 2008, according to new research from healthcare market research firm Decision Resources.

Automated CPR Improves Survival—before and during PCI

Its increasingly clear that improved outcomes after an out-of-hospital cardiac arrest depend on having a host of protocols in place, rather than relying on one therapy or benchmark. Heres a look at automated CPR devices in the treatment of sudden cardiac arrest.

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