Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

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Women underrepresented in clinical trials for heart failure, acute coronary syndrome

While women are equally or overrepresented in clinical trials for hypertension, atrial fibrillation (AFib) and pulmonary arterial hypertension, they are underrepresented in clinical trials for heart failure, coronary artery disease and acute coronary syndrome, according to a new study published in the Journal of the American College of Cardiology.

Eidos Therapeutics Initiates Phase 2 Clinical Trial for AG10 Targeting Transthyretin Amyloidosis Cardiomyopathy

SAN FRANCISCO, May 3, 2018 /PRNewswire/ — Eidos Therapeutics, Inc., a clinical stage biopharmaceutical company developing a novel oral therapy to treat transthyretin (TTR) amyloidosis (ATTR), today announced dosing of the first patient in the Phase 2 clinical trial of AG10 in patients with ATTR cardiomyopathy.

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Abbott’s XIENCE Sierra stent to be reimbursed through insurance in Japan

Abbott’s XIENCE Sierra, the newest generation of the company’s everolimus-eluting coronary stent, has been approved for national reimbursement in Japan.

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AHA/ASA retracts large portion of new stroke guidelines

The American Heart Association (AHA)/American Stroke Association (ASA) is revisiting its recently updated stroke guidelines after issuing a “correction” that removed several portions.

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Bystander CPR, defibrillation only helpful for finite period

A new nationwide study from Japan highlighted the importance of timely ambulance arrival, showing that bystander defibrillation and cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest are essentially worthless if EMS response times are slower than 13 minutes and 11 minutes, respectively.

Psoriasis treatments can decrease coronary plaque

Common therapies used in the treatment of psoriasis may help reduce coronary plaque, according to a new study presented April 26 at the Society for Cardiovascular Angiography and Interventions (SCAI) 2018 Scientific Sessions in San Diego.

Genetically modified thrombolytic boosts reperfusion after stroke

Alteplase is sometimes administered to dissolve clots before endovascular thrombectomy in patients with ischemic stroke. But a new study in the New England Journal of Medicine demonstrates tenecteplase, a genetically modified form of alteplase, is associated with better blood flow restoration and improved functional outcomes.

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Novel device treats pulmonary embolism without clot-dissolving drugs

A new device allows clinicians to remove blood clots from the pulmonary arteries and improve right ventricular function without the use of thrombolytics, according to a late-breaking clinical study presented April 26 at SCAI 2018 in San Diego.

Around the web

Several key trends were evident at the Radiological Society of North America 2024 meeting, including new CT and MR technology and evolving adoption of artificial intelligence.

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.