ACC announces late-breaking clinical trials sessions for 66th annual meeting
The American College of Cardiology (ACC) has announced the late-breaking clinical trials schedule for its 66th annual scientific session & expo.
The conference takes place from March 17 to March 19 at the Walter E. Washington Convention Center in Washington, D.C.
Here is a list of the late-breaking sessions (all times are Eastern Standard Time):
Friday, March 17
Title: ACC.17 Opening Showcase and the Joint ACC/JACC Late-Breaking Clinical Trials
Room: Main Tent, Hall D
Time: 8:00 a.m. to 10:00 a.m.
* FOURIER: Primary Results of the Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER) Trial
* SPIRE 1 and SPIRE 2: Safety and Cardiovascular Event Efficacy of Bococizumab Among 27,000 High Risk Patients
* SURTAVI: Transcatheter Aortic Valve Replacement With a Self-Expanding Bioprosthesis Compared With Surgical Aortic Valve Replacement in Patients at Intermediate Surgical Risk: First Results From the SURTAVI Clinical Trial
Friday, March 17
Title: Featured Clinical Research I
Room: 146B
Time: 12:15 p.m. to 1:45 p.m.
* RESET-HCM: Testing Safety and Efficacy: The Randomized Exploratory Study of Exercise Training in Hypertrophic Cardiomyopathy
* S2P Study: Results of MRI-Based Screening Study of 5130 Candidates for Sports Participation
* MR-INFORM: Stress Perfusion Imaging to Guide the Management of Patients With Stable Coronary Artery Disease
* Effects of Different Front-of-Pack Food Labelling Formats on the Healthiness of Food Purchases — a Randomized Trial
* Native South American Tsimane Have the Lowest Levels of Coronary Atherosclerosis Ever Reported
* ORION 1: LDL-C Reduction From 6 to 9 Months Following Single or Second Injection of Inclisiran a Novel siRNA Compound: Primary Efficacy and Safety Outcomes of the ORION 1 Trial
Saturday, March 18
Title: Joint American College of Cardiology/Journal of the American Medical Association Late-Breaking Clinical Trials
Room: Main Tent, Hall D
Time: 8:00 a.m. to 9:15 a.m.
* EINSTEIN CHOICE: Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism
* GEMINI-ACS-1: A Randomized Trial Evaluating Clinically Significant Bleeding With Low-Dose Rivaroxaban Versus Aspirin, in Addition to P2Y12 Inhibition, for Patients After Acute Coronary Syndromes
* REACH: e-Counseling for Self-Care Adherence Adds Therapeutic Benefit for Hypertension: The REACH Trial
* CARAT: Effect of Serial Infusions of CER-001, a Pre-Beta High-Density Lipoprotein Mimetic on Coronary Atherosclerosis: Results of the CARAT Study
* EBBINGHAUS: Primary Results of EBBINGHAUS, a Cognitive Study of Patients Enrolled in the FOURIER Trial
Saturday, March 18
Title: Late-Breaking Clinical Trials
Room: Main Tent, Hall D
Time: 10:45 a.m. to 12:00 p.m.
* COMPARE-ACUTE: FFR Guided Acute Complete Revascularization Versus Culprit Lesion Only Treatment in Patients Presenting With ST-Segment Elevation Myocardial Infarction and Multi Vessel Disease
* DEFINE-FLAIR: Primary Results of DEFINE-FLAIR: A Multi-Centre, Prospective, International, Randomized, Blinded Comparison of Clinical Outcomes and Cost Efficiencies of iFR and FFR Decision-Making for Physiological Guided Coronary Revascularization
* IFR-SWEDEHEART: Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve Guided Intervention (IFR-SWEDEHEART): A Multicenter, Prospective, Registry-Based Randomized Clinical Trial
* DECISION CTO: Drug-Eluting Stent Versus Optimal Medical Therapy in Patients With Coronary Chronic Total Occlusion: DECISION CTO Randomized Trial
* ABSORB III: Everolimus-Eluting Bioresorbable Vascular Scaffolds in Patients With Coronary Artery Disease: Two-Year Outcomes From the ABSORB III Trial
Saturday, March 18
Title: Featured Interventional Clinical Research II
Room: 201
Time: 12:30 p.m. to 1:45 p.m.
* ADVICE Study: Real-World Comparative Effectiveness of Transcatheter Versus Surgical Aortic Valve Replacement in the United States: An Analysis from Two US Registries Linked to Medicare Data
* STS/ACC TVT Registry: Comparison of In-Hospital and 1-Year Outcomes of Transcatheter Aortic Valve Replacement for Failed Surgical Bioprosthesis Versus Native Aortic Stenosis From the STS/ACC TVT Registry
* Procedural and Clinical Outcomes in Transcatheter Aortic Valve Replacement for Bicuspid Versus Tricuspid Aortic Valve Stenosis
* RAD Matrix: Radiation Exposure and Vascular Access in Acute Coronary Syndromes: The RAD Matrix Study
* Clinical Outcomes at 1-Year After Commercial Transcatheter Mitral Valve Repair in the United States
Sunday, March 19
Title: Joint American College of Cardiology/New England Journal of Medicine Late-Breaking Clinical Trials
Room: Main Tent, Hall D
Time: 8:00 a.m. to 9:15 a.m.
* LEVO-CTS: Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery With Cardiopulmonary Bypass: Primary Results of the LEVO-CTS Trial
* Cerebral Embolic Protection Devices During Surgical Aortic Valve Replacement: A Randomized Trial From the Cardiothoracic Surgical Trials Network
* Silent Cerebral Microbleeds During TAVR: Insight From a Prospective Cerebral MRI Cohort
* RESOLVE and SAVORY: Subclinical Leaflet Thrombosis in Transcatheter and Surgical Bioprosthetic Aortic Valves: Results From RESOLVE and SAVORY Registries
* VISION Study: Relationship Between High Sensitive Troponin T Measurements and 30-Day Mortality After Noncardiac Surgery
Sunday, March 19
Title: Late-Breaking Clinical Trials
Room: Main Tent, Hall D
Time: 10:45 a.m. to 12:00 p.m.
* RE-CIRCUIT: Safety and Efficacy of Uninterrupted Anticoagulation With Dabigatran Etexilate Versus Warfarin in Patients Undergoing Catheter Ablation of Atrial Fibrillation: The RE-CIRCUIT Study
* ARISTOTLE: Digoxin and Mortality in Patients With Atrial Fibrillation With and Without Heart Failure: Does Serum Digoxin Concentration Matter?
* Comparative Effectiveness of Left Atrial Appendage Occlusion Among Atrial Fibrillation Patients Undergoing Cardiac Surgery: A Report From the Society of Thoracic Surgeons Adult Cardiac Surgery Database
* GIFT of Warfarin: Benefit of Pharmacogenetic Dosing
* SPAIN Study: Randomized Placebo Controlled Trial of Closed Loop Stimulation in Recurrent Reflex Vasovagal Syncope
Sunday, March 19
Title: Featured Clinical Research III
Room: 150A
Time: 2:00 p.m. to 3:30 p.m.
* Early Challenges for PSCK9 Inhibitor Prescriptions and Patients: Rejections and Rates Unfilled
* STOMP: The Effect of High-Dose Atorvastatin on Neuronal Activity and Cognitive Function
* Outcomes for 15,259 US Patients With Acute MI Cardiogenic Shock (AMICS) Supported With Impella
* CVD-REAL Study: Lower Rates of Hospitalization for Heart Failure in New Users of SGLT-2 Inhibitors Versus Other Glucose Lowering Drugs — Real-World Data From Four Countries and More Than 360,000 Patients: The CVD-REAL Study
* Paroxysmal Atrial Fibrillation Is Associated With Worse Clinical Outcomes Than Persistent/Permanent Atrial Fibrillation in Patients With Heart Failure and Reduced Ejection Fraction
* Reduction in Heart Failure Hospitalizations With Ambulatory Hemodynamic Monitoring Seen in Clinical Trials Is Maintained in the ‘Real World’