Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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1 in 5 patients in cardiac rehab are depressed, anxious or stressed

Around one in five heart patients in cardiac rehabilitation are depressed, anxious or stressed, according to a new study published in the European Journal of Preventive Cardiology.

Analysis adds to evidence of an ‘obesity paradox’ in heart failure

Evidence published in BMJ Heart last month supports the idea of an “obesity paradox” in heart failure, further complicating a long-running debate as to whether extra weight can be cardioprotective in patients with established CVD.

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Communication training improves end-of-life discussions between HF patients, physicians

A 90-minute communication skills course improved conversations about ICD deactivation and goals of care between clinicians and their patients, according to the recently published results of the WISDOM study.

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Cardiac amyloidosis increasingly common in US

New research suggests the incidence of cardiac amyloidosis in the U.S. is trending up, bringing with it high rates of morbidity and mortality.

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Dapagliflozin fast-tracked again—this time to treat heart failure

Just weeks after it fast-tracked dapagliflozin for the treatment of chronic kidney disease, the FDA announced it was granting Fast Track status to the drug for another indication: heart failure.

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Malaria tied to 30% increased risk of HF

Research presented at the ESC Congress in Paris Sept. 2 suggests malaria could be linked to as much as a 30% increased risk of heart failure.

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Study suggests women are overmedicated for heart failure

Research out of the Netherlands suggests current clinical guidelines might recommend overtreatment for women with heart failure, who see maximum benefit from HF drugs at half the dose of men.

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SGLT2 inhibitors cut heart failure risk for T2D patients

SGLT2 inhibitors—namely dapagliflozin—have been linked to a reduced risk of heart failure and death, as well as decreased odds of major adverse cardiovascular events.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.